This Chicken Penne Casserole is more than just comfort food; it’s a cherished tradition, a hallmark of Midwest kitchens, where each bite brings memories of family gatherings, laughter, and the warmth of home. This is the casserole that graced countless family tables, perfect for those chilly evenings when you crave a dish that feels like a hug from grandma. Picture tender chicken chunks, a creamy sauce, and a bubbly, cheese-crusted top – all baked together in a delicious, heartwarming embrace.
Pairs perfectly with a crisp green salad, steamed green beans, or buttery corn. And for a sweet finish, an old-fashioned slice of apple pie keeps that Midwest spirit alive.
Servings: 6 hearty portions
Ingredients:
- 12 ounces penne pasta
- 2 cups cooked chicken, diced
- 1 can (10.5 ounces) cream of chicken soup
- 1 cup sour cream
- 1/2 cup milk
- 1/2 teaspoon garlic powder
- 1/2 teaspoon onion powder
- 1 teaspoon dried parsley
- Salt and pepper to taste
- 2 cups shredded cheddar cheese
- 1/2 cup breadcrumbs
- 2 tablespoons butter, melted
Directions:
- Preheat & Prep: Heat oven to 350°F. Butter a 9×13 inch baking dish.
- Cook Pasta: In a large pot of salted water, cook the penne until al dente (it will finish cooking in the oven).
- Combine Ingredients: Drain pasta, and in the same pot, mix the cooked penne with diced chicken, cream of chicken soup, sour cream, milk, garlic powder, onion powder, and parsley. Season with salt and pepper to taste.
- Layer: Pour half of the mixture into the baking dish, top with 1 cup of shredded cheese, then add the remaining pasta mixture.
- Top with Cheese & Breadcrumbs: Sprinkle the rest of the cheese over the top. In a small bowl, combine breadcrumbs with melted butter, then spread evenly over the casserole for added crunch.
- Bake: Place in the oven and bake for 25-30 minutes, or until the casserole is bubbling around the edges and the top is golden-brown.
- Rest & Serve: Let it rest briefly after baking – good things are worth the wait.
Variations & Tips:
- Add Veggies: Stir in mushrooms, peas, or any favorite vegetables for extra flavor and nutrition.
- For a Kick: Add a pinch of red pepper flakes.
- Quick Tip: Leftover rotisserie chicken works well and saves time.
- Gluten-Free Option: Substitute gluten-free penne for a seamless swap.
- Make-Ahead Friendly: This casserole freezes beautifully. Just cover tightly before baking, then thaw overnight in the fridge and bake as directed.